Ananthanarayanan Kumar

Ananthanarayanan Kumar

  • Alumni
  • India
  • 2015 PhD Biological Science @ MRC LMB
  • Churchill College

Structural studies of molecular machines and their assembly are my primary research interest. Ever since my Bachelors thesis project at Trans-Membrane Trafficking lab at OIST (Japan), I have been amazed by the tricky membrane proteins and the complexity behind their structural studies. My Masters thesis work at the Bio-membrane Functions Lab in Nagoya University (Japan) involved the functional and structural analysis of a flagellar inner membrane protein from Vibrio alginolyticus. During my Masters, I worked closely with Imada sensei's lab at Osaka University to learn X-ray crystallography. Next, as a summer intern at the Mancini lab at STRUBI (Oxford University), I developed a desire to know more about structural dissection of pathways associated with gene regulation such as Chromatin remodelling and mRNA processing. This led me to pursue my PhD research at the Passmore lab in MRC LMB with a GATES Cambridge scholarship. During my PhD, using an integrative structural biology approach, I unraveled the structural architecture of the eukaryotic mRNA 3' end polyadenylation machinery ( I specialise in using a combination of in vitro biochemistry, cryo-EM and NMR to study the structure and dynamics of protein-RNA complexes associated with fundamental cellular processes. I am now pursuing my postdoc research at the Pyle lab, MCDB, Yale University.

Previous Education

SASTRA University
Nagoya University